
Third-Party Tested by Verum Analytics
MOTS-c
Mitochondrial-derived research peptide encoded within the 12S rRNA gene.
Third-Party Tested by Verum Analytics

Albert's Verdict
MOTS-c is the only mitochondrial-derived peptide I know of that translocates to the nucleus under metabolic stress — it's essentially your mitochondria sending an SOS that triggers whole-body adaptation. The insulin sensitivity data at 12 weeks is hard to ignore.
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Arrives as lyophilized (powder) form
Shipped freeze-dried for maximum stability and shelf life. See laboratory preparation guide for handling instructions.
Product Description
MOTS-c (Mitochondrial Open Reading Frame of the Twelve S rRNA type-c) is a 16-amino-acid mitochondria-derived peptide (MDP) encoded within the mitochondrial genome. Discovered in 2015, it is studied in laboratory research models of mitochondrial-nuclear signaling.
Molecular Profile:
- Molecular Weight: 2,174.6 g/mol
- Length: 16 amino acids
- Sequence: MRWQEMGYIFYPRKLR
- Origin: Mitochondrial 12S rRNA gene
Research Applications:
- AMPK pathway research models
- Cellular glucose metabolism and insulin-signaling research models
- Mitochondrial-nuclear retrograde signaling research
- Aging-associated metabolic pathway research
- Folate-methionine cycle and epigenetic pathway research
- Skeletal muscle cellular research models
Quality Standards:
- Purity: ≥99% verified by HPLC
- Third-party tested with COA included
For laboratory handling instructions, refer to the Preparation Guide.
FOR RESEARCH USE ONLY. Not for human or animal consumption.
Technical Specifications
- Molecular Formula
- C101H152N28O22S2
- Molecular Weight
- 2174.64 g/mol
- Sequence
- Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
Frequently Researched Together
Commonly studied alongside in laboratory settings
Learn More About This Peptide
Research Use Only: This product is intended for laboratory research purposes only. Not for human consumption.