Third-Party Tested by Verum Analytics
IGF-1 LR3
Long R3 variant of Insulin-like Growth Factor 1 with extended half-life.
Third-Party Tested by Verum Analytics
Albert's Verdict
The LR3 modification extends the half-life to roughly 20–30 hours versus the native form's minutes — that sustained receptor occupancy is what makes the downstream mTOR and PI3K signaling data so interesting. Worth the wait when it's back in stock.
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Arrives as lyophilized (powder) form
Shipped freeze-dried for maximum stability and shelf life. See laboratory preparation guide for handling instructions.
Product Description
IGF-1 LR3 (Long R3 Insulin-Like Growth Factor-1) is an 83-amino acid synthetic analog of IGF-1 with an arginine substitution at position 3 and a 13-amino acid N-terminal extension. These modifications significantly reduce binding to IGF binding proteins (IGFBPs), resulting in enhanced bioavailability and a substantially longer half-life compared to native IGF-1.
Molecular Profile:
- Molecular Weight: 9,111 g/mol
- Length: 83 amino acids (vs. 70 for native IGF-1)
- Modification: Arg³ substitution + 13-AA N-terminal extension
- CAS Number: 946870-92-4
Research Applications:
- Cell proliferation and hyperplasia studies
- Muscle satellite cell activation research
- IGFBP-independent IGF-1 receptor signaling
- Glucose uptake and insulin sensitization pathways
- Protein synthesis and nitrogen balance models
- Anti-apoptotic mechanism investigation
Quality Standards:
- Purity: ≥99% verified by HPLC
- Third-party tested with COA included
FOR RESEARCH USE ONLY. Not for human consumption.
Technical Specifications
- Molecular Formula
- C400H625N111O115S9
- Molecular Weight
- 9117.5 g/mol
- Sequence
- 83 amino acid sequence
Frequently Researched Together
Commonly studied alongside in laboratory settings
Learn More About This Peptide
Research Use Only: This product is intended for laboratory research purposes only. Not for human consumption.